The only dyssomnia that often requires drug therapy is:

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Narcolepsy is the only dyssomnia that often requires drug therapy, as it is a neurological disorder that affects the brain's ability to regulate sleep-wake cycles. Medications such as stimulants and antidepressants may be used to treat symptoms of excessive daytime sleepiness and cataplexy, which are common in narcolepsy. Other dyssomnias may require non-pharmacological treatments such as sleep hygiene education, cognitive behavioral therapy, or treatment of underlying medical conditions.

The Only Dyssomnia That Often Requires Drug Therapy Is