Generally,L-thyroxine is preferable to liothyronine as therapy in hypothyroid states because:

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Quizplus · Accepted Answer

L-thyroxine has a longer duration of action, which allows for less frequent dosing and more stable hormone levels. It is also less cardiotoxic than liothyronine, meaning it has less potential for adverse effects on the heart. Additionally, monitoring hormone levels is easier with L-thyroxine therapy. Therefore, all of the above reasons make L-thyroxine preferable to liothyronine as therapy in hypothyroid states.

Generally,L-Thyroxine Is Preferable to Liothyronine as Therapy in Hypothyroid States