Radiographic findings of supernumerary epiphyses in the hands and feet, severe kyphoscoliosis, and narrowed interpediculate distance in the spine, especially in the lumbar region, would lead a clinician to suspect __________.

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The radiographic findings described are characteristic of diastrophic dysplasia, a rare genetic disorder affecting cartilage and bone growth. Supernumerary epiphyses (extra growth centers) in the hands and feet are one of the diagnostic features, as well as spinal abnormalities such as severe kyphoscoliosis and narrowed interpediculate distance. Achondroplasia is also a genetic disorder affecting bone growth but is characterized by short stature and specific radiographic findings such as a large head with a small facial profile and prominent forehead. Epiphyseal dysplasia is a group of genetic disorders affecting joint cartilage and growth plate development, but its radiographic findings are typically more specific to the affected joint(s). Cleidocranial dysplasia is a genetic disorder affecting bone and teeth development, but its radiographic findings involve the skull, clavicles, and dental abnormalities.

Radiographic Findings of Supernumerary Epiphyses in the Hands and Feet