The pathological manifestations of osteopetrosis is related to __________.

Question

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Osteopetrosis is a rare genetic disorder characterized by defective osteoclastic activity, leading to an increase in bone density and a decrease in bone marrow space. This results in various pathological manifestations such as skeletal deformities, neurological complications, and hematological abnormalities. Increased osteoclastic activity (choice A) would lead to bone resorption and osteoporosis, which is the opposite of osteopetrosis. Increased osteoblastic activity (choice C) would lead to increased bone formation and density, but this is not the cause of osteopetrosis. Similarly, decreased osteoblastic activity (choice D) would also lead to decreased bone formation and density, but this is not the primary defect in osteopetrosis.

The Pathological Manifestations of Osteopetrosis Is Related to __________