How sensitive is gel electrophoresis when it is used to separate DNA?
A)It can separate fragments of DNA that differ grossly in size.
B)It can separate really big DNAs from very small DNAs.
C)It can separate DNAs that differ by hundreds of nucleotides.
D)It can separate DNA molecules that vary in length by only a single nucleotide.
E)It can separate DNA molecules that vary in length by five or more nucleotides.

Question

Quizplus · Accepted Answer

Gel electrophoresis is very sensitive and can separate DNA molecules that differ in length by only a single nucleotide. This is because the gel matrix acts as a molecular sieve, allowing smaller molecules to move more easily through the gel and separate from larger molecules. This can be especially useful in genetic testing and analysis, where even small variations in DNA sequence can have significant implications.

How Sensitive Is Gel Electrophoresis When It Is Used to Separate