Which heterotrimeric G proteins function by inhibiting adenylyl cyclase? A)G_s family B)G_q family C)G_i family D)G_12/13family E)G_r family

Question

Quizplus · Accepted Answer

The G_i family of heterotrimeric G proteins function by inhibiting adenylyl cyclase. This is achieved through the inhibition of the alpha subunit of the G protein, which decreases the activity of adenylyl cyclase and ultimately reduces the production of cyclic AMP (cAMP) in the cell. Other families of G proteins, such as the G_s family, function by activating adenylyl cyclase and increasing cAMP production.

Which Heterotrimeric G Proteins Function by Inhibiting Adenylyl Cyclase