How can the replication of both DNA strands by two tethered polymerases be accomplished when the template strands run in opposite directions?
A)One of the enzymes polymerizes DNA in the 3'-5' direction.
B)The DNA of the lagging strand loops back on itself so it has same orientation as the leading strand template.
C)The DNA of the leading strand loops back on itself so it has same orientation as the lagging strand template.
D)The lagging strand is broken and then rejoined regularly to allow simultaneous synthesis.
E)It just is.

Question

How can the replication of both DNA strands by two tethered polymerases be accomplished when the template strands run in opposite directions?
A)One of the enzymes polymerizes DNA in the 3'->5' direction.
B)The DNA of the lagging strand loops back on itself so it has same orientation as the leading strand template.
C)The DNA of the leading strand loops back on itself so it has same orientation as the lagging strand template.
D)The lagging strand is broken and then rejoined regularly to allow simultaneous synthesis.
E)It just is.

Quizplus · Accepted Answer

The replication of both DNA strands by two tethered polymerases can be accomplished when the template strands run in opposite directions by looping back the DNA of the lagging strand on itself so that it has the same orientation as the leading strand template. This allows both polymerases to synthesize new DNA strands in the 5' to 3' direction.

How Can the Replication of Both DNA Strands by Two