When histone deacetylase proteins (HDACs)are recruited to a genetic locus,what events are likely to happen?
A)histone and/or DNA methylation
B)transcriptional activation
C)transcriptional repression
D)a and b
E)a and c

Question

Quizplus · Accepted Answer

When histone deacetylase proteins (HDACs) are recruited to a genetic locus, they remove acetyl groups from histones, leading to the compaction of chromatin and making it difficult for transcription machinery to access the DNA. This results in transcriptional repression. Additionally, HDACs are often associated with other chromatin-modifying enzymes that promote DNA methylation, leading to further transcriptional repression. Thus, both histone and DNA methylation occur in the presence of HDACs, leading to transcriptional repression.

When Histone Deacetylase Proteins (HDACs)are Recruited to a Genetic Locus,what