What chemical group is attached to the first methionine in a polypeptide chain in prokaryotes?
A)a formyl group
B)a methyl group
C)an acetyl group
D)a phosphate group
E)a glutamyl group

Question

Quizplus · Accepted Answer

In prokaryotes, the first methionine in a polypeptide chain is usually modified by the addition of a formyl group (CHO-) through a formylation reaction involving the enzyme transformylase. This process is known as N-formylation and is important for proper protein targeting and function.

What Chemical Group Is Attached to the First Methionine in a Polypeptide