Bardet‐Biedl syndrome (BBS)is caused by mutations in any one of a number of genes that affect protein trafficking into cilia. Persons afflicted with BBS exhibit a remarkable range of abnormalities, like polydactyly, obesity, kidney disease, etc. These disparatesymptoms are thought to reflect the function of cilia ________________.
A)as sensors for a magnetic field
B)aslocomotory organelles
C)as sources of flagella
D)as binding sites for actin
E)as antennas to receive signals that regulate development and physiology

Question

Quizplus · Accepted Answer

Cilia are known to function as "antennas," receiving signals that regulate various developmental and physiological processes in the body. This is likely why BBS, which affects protein trafficking into cilia, results in such a wide range of disparate symptoms.

Bardet‐Biedl Syndrome (BBS)is Caused by Mutations in Any One of a Number