You genetically engineer nonadhesive cells to express one variety of cadherins and then mix the cells in various combinations.You then monitor their interactions.What do you observe?
A)The genetically engineered cells adhered preferentially to cells expressing one of the other cadherins.
B)The genetically engineered cells adhered preferentially to cells expressing the same cadherins.
C)The genetically engineered cells did not stick to any other cells.
D)The genetically engineered cells died.
E)The genetically engineered cells migrated to a different location.

Question

Quizplus · Accepted Answer

Cells expressing the same variety of cadherins will preferentially adhere to each other due to the specificity of their binding. This is the basis of cell sorting and tissue formation during development. However, it is possible that the genetically engineered cells may also exhibit some degree of adhesion to cells expressing other cadherins, particularly if the differences between the cadherins are minor. Therefore, choice A is not entirely incorrect, but choice B is more accurate. Choices C, D, and E are not likely outcomes of this experiment.

You Genetically Engineer Nonadhesive Cells to Express One Variety of Cadherins