Which of the following genetic diseases is characterized by fragile, abnormally shaped erythrocytes and has been traced to mutations in ankyrin or spectrin?
A)hemophilia
B)sickle cell anemia
C)hemolytic anemias
D)leukemia
E)erythroblastosis

Question

Quizplus · Accepted Answer

The genetic disease characterized by fragile, abnormally shaped erythrocytes is hemolytic anemias, and specifically hereditary spherocytosis. This disease has been traced to mutations in ankyrin, spectrin, or other proteins involved in the structure of the erythrocyte membrane. Hemophilia is a bleeding disorder, sickle cell anemia is a disease where erythrocytes are sickle-shaped, and leukemia is a cancer of blood-forming tissues. Erythroblastosis is a condition where maternal antibodies attack fetal erythrocytes, leading to hemolysis.

Which of the Following Genetic Diseases Is Characterized by Fragile