Which of the following tripeptides would be most likely to be soluble in an organic (hydrophobic)solvent like benzene?

Question

Quizplus · Accepted Answer

The tripeptide N-proline-phenylalanine-leucine-C has hydrophobic amino acids on both ends (proline and leucine) and a hydrophilic amino acid in the middle (phenylalanine). This arrangement makes it less likely to form strong hydrogen bonds with water molecules and more likely to have strong interactions with hydrophobic solvents such as benzene. The other options all contain charged or polar amino acids that would be more likely to interact with water molecules and less likely to dissolve in hydrophobic solvents.

Which of the Following Tripeptides Would Be Most Likely to Be