What recruits cytoplasmic GRKs (G protein-coupled receptor kinases)to the plasma membrane?
A)inhibition of certain G proteins
B)destruction of the GPCRs
C)activation of GPCRs
D)inhibition of the GPCRs
E)destruction of the hormone

Question

Quizplus · Accepted Answer

Activation of GPCRs recruits cytoplasmic GRKs to the plasma membrane. GRKs phosphorylate the activated GPCR, leading to its desensitization and internalization. This helps to prevent excessive cellular responses to prolonged receptor activation.

What Recruits Cytoplasmic GRKs (G Protein-Coupled Receptor Kinases)to the Plasma