What is used to maintain the Ran-GTP gradient across the nuclear envelope? A)energy released by ATP hydrolysis B)a proton gradient C)a H⁺ ion gradient D)energy released by GTP hydrolysis E)energy released by GDP hydrolysis

Question

Quizplus · Accepted Answer

The maintenance of the Ran-GTP gradient across the nuclear envelope is facilitated by the energy released by GTP hydrolysis. GTPase-activating proteins (GAPs) present in the cytoplasmic side of the nuclear envelope promote the hydrolysis of Ran-GTP to Ran-GDP, which is then transported back to the nucleus by importins. On the other hand, Guanine nucleotide exchange factors (GEFs) present in the nucleoplasm promote the exchange of GDP for GTP on Ran, thus helping to maintain the gradient.

What Is Used to Maintain the Ran-GTP Gradient Across the Nuclear