Susumu Ohno proposed that the evolution of vertebrates from a much simpler invertebrate ancestor was made possible by two separate rounds of whole-genome duplication during an early evolutionary period. How was it proposed that the whole-gene duplication led to the encoding of the more complex vertebrate body?

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The theory proposed by Susumu Ohno suggests that the additional genes generated by the whole-genome duplication would have provided the raw material for the evolution of more complex vertebrate body plans, as these genes could be gradually modified and molded over evolutionary time to serve new functions and create novel structures. This process is known as neofunctionalization and is thought to have played a key role in the evolution of many complex traits in vertebrates.

Susumu Ohno Proposed That the Evolution of Vertebrates from a Much