Cells are infected with a vesicular stomatitis virus (VSV)strain in which a viral gene (VSVG)is fused to the green fluorescent protein gene. When the chimeric protein is synthesized, what pathway does it follow from synthesis until it leaves the cell?
A)RER, Golgi complex, plasma membrane, viral envelopes
B)RER, Golgi complex, viral envelopes, plasma membrane
C)Golgi complex, RER, plasma membrane, viral envelopes
D)RER, Golgi complex, mitochondria, plasma membrane, viral envelopes
E)RER, mitochondria, Golgi complex, plasma membrane, viral envelopes

Question

Quizplus · Accepted Answer

The chimeric protein synthesized in cells infected with a vesicular stomatitis virus (VSV) strain that includes a viral gene fused to the green fluorescent protein gene follows the secretory pathway. This pathway starts with synthesis in the rough endoplasmic reticulum (RER), then moves to the Golgi complex for further processing, is transported to the plasma membrane, and finally becomes part of the viral envelopes as the virus assembles and buds off from the cell.

Cells Are Infected with a Vesicular Stomatitis Virus (VSV)strain in Which