What determines the specificity of vesicle fusion to a target membrane?
A)interactions between tethering proteins alone
B)interactions between Rabs alone
C)interactions between specific combinations of interacting proteins,including tethering proteins,Rabs and SNAREs assembled at that site in the cell
D)interactions between SNAREs alone
E)a single protein in the membrane of the particular vesicle and target membrane

Question

Quizplus · Accepted Answer

The specificity of vesicle fusion to a target membrane is determined by specific combinations of interacting proteins, including tethering proteins, Rabs, and SNAREs assembled at that site in the cell. While interactions between tethering proteins (A), Rabs (B), and SNAREs (D) all play a role in vesicle fusion, it is the specific combination of these proteins that results in the correct vesicle fusion. A single protein (E) alone would not be sufficient to determine specificity.

What Determines the Specificity of Vesicle Fusion to a Target