What leads to the degradation of the contents of late endosomes by lysosomal enzymes?
A)secretion of lysosomal enzymes into late endosomes
B)transport of lysosomal enzymes into late endosomes through specialized pore complexes
C)fusion of late endosomes containing intralumenal vesicles with a lysosome
D)fusion of early endosomes with lysosomes; late endosomes lowering their internal pH activating the enzymes
E)late endosomes synthesizing lysosomal enzymes that then degrade the contents

Question

Quizplus · Accepted Answer

The degradation of the contents of late endosomes is achieved by the fusion of late endosomes with lysosomes. This leads to the formation of an intermediate organelle known as the endolysosome, where the luminal contents of the late endosome are degraded by lysosomal enzymes. The degradation is made possible by the transport of lysosomal enzymes into the endolysosome through specialized pore complexes. This process is facilitated by the presence of intralumenal vesicles within the late endosome, which increase the surface area available for the fusion with lysosomes.

What Leads to the Degradation of the Contents of Late