Why does glucocerebrosidase taken into macrophages by receptor-mediated endocytosis end up in lysosomes?
A)The enzyme travels through the cytoplasm to get to lysosomes.
B)The enzyme denatures and then goes through a channel into lysosomes.
C)Lysosomes are the natural target of enzymes taken into macrophages by endocytosis.
D)Lysosomes adsorb glucocerebrosidase to their surfaces.
E)Lysosomes pick up the enzyme from mitochondria.

Question

Quizplus · Accepted Answer

Lysosomes are the natural target for endocytosed macromolecules and enzymes in macrophages. Once inside the macrophage, glucocerebrosidase will be targeted to lysosomes for degradation or recycling.

Why Does Glucocerebrosidase Taken into Macrophages by Receptor-Mediated Endocytosis End