Type I collagen mutations cause a potentially lethal condition characterized by extremely fragile bones,thin skin and weak tendons.This condition is called _______.
A)osteogenesis imperfecta
B)Ehler-Danlos syndrome
C)Alport syndrome
D)dwarfism and skeletal deformities
E)diabetes

Question

Quizplus · Accepted Answer

Type I collagen is the most abundant collagen in the body and mutations in this gene can cause osteogenesis imperfecta, which is characterized by weakened bones, thin skin, weak tendons, and other connective tissues. Ehler-Danlos syndrome is also a genetic disorder affecting collagen, but it is caused by mutations in other types of collagen genes and has different symptoms. Alport syndrome affects proteins in the kidneys, ears, and eyes, not collagen. Dwarfism and skeletal deformities are caused by various genetic and environmental factors, not exclusively collagen mutations. Diabetes is a metabolic disorder and not directly related to collagen.

Type I Collagen Mutations Cause a Potentially Lethal Condition Characterized