Lymphocytes are isolated and labeled with radioactive isotopes.They are then exposed to frozen tissue sections of a lymphoid organ.What happens?
A)The lymphocytes bind uniformly to the sections.
B)The lymphocytes bind to each other.
C)The lymphocytes selectively adhere to the endothelial lining of venules in peripheral lymph nodes.
D)The lymphocytes selectively adhere to the endothelial lining of arterioles in peripheral lymph nodes.
E)The lymphocytes do not stick to the sections.

Question

Quizplus · Accepted Answer

The selective adherence of lymphocytes to endothelial lining of venules in peripheral lymph nodes is known as homing. This process is essential for lymphocytes to migrate from blood to lymphoid organs. The adherence is selective in nature, as lymphocytes recognize and bind to specific adhesion molecules expressed on endothelial cells of venules in lymphoid organs. Therefore, the lymphocytes in this experiment would selectively adhere to the endothelial lining of venules in the frozen tissue sections.

Lymphocytes Are Isolated and Labeled with Radioactive Isotopes