How was the asymmetry of membrane lipids discovered?
A)The lipid asymmetry was visualized in the electron microscope.
B)The lipid asymmetry was observed with a special stain in the light microscope.
C)Treatment of intact red blood cells with phospholipases.
D)Treatment of intact red blood cells with trypsin.
E)Treatment of liver cells with phospholipases.

Question

Quizplus · Accepted Answer

The asymmetry of membrane lipids was discovered by treating intact red blood cells with phospholipases, which can only access lipids on the outer leaflet of the membrane, revealing differences in lipid composition between the inner and outer leaflets.

How Was the Asymmetry of Membrane Lipids Discovered