Cytotoxic T lymphocytes (CTLs)killing of virus infected target cells depends on which of the following molecules?
A)Interferon g
B)Complement C9
C)Perforin
D)IL-17
E)CD40L

Question

Quizplus · Accepted Answer

When a CTL recognizes viral peptide-MHC on an infected cell surface,it is activated to release the contents of its cytosolic granules,which contain perforin and granzymes.Perforin is a membrane-disrupting protein that inserts into the infected cell plasma membrane,and facilitates the entry of the granzymes into the cytosol of the infected cell.Granzymes then activate apoptosis of the infected cell.

Cytotoxic T Lymphocytes (CTLs)killing of Virus Infected Target Cells Depends