For each feature of self-tolerance described in questions ,choose the term (letters A-K)that most closely matches it.
-Site of central T cell tolerance induction
A)Immature (IgM+IgD-)
B)Thymic cortex
C)Bone marrow
D)Antigen recognition without T cell help
E)Receptor editing
F)Activation-induced cell death
G)Regulatory T cell-mediated suppression
H)Antigen recognition with costimulation
I)Double positive (CD4+CD8+)
J)Anergy
K)Thymic medulla

Question

Quizplus · Accepted Answer

Double-positive T cells,which are the cells susceptible to central T cell tolerance induction,are found in the thymic cortex.The developing T cells that are not deleted at the double-positive stage mature into single-positive (CD4+ or CD8+)thymocytes and migrate into the medulla before exiting the thymus.

For Each Feature of Self-Tolerance Described in Questions ,Choose the Term