Match the definitions in questions with the mast cell mediator (A-G)that most closely matches it.
-Cyclooxygenase-pathway product of arachidonic acid metabolism that causes vascular dilatation,smooth muscle contraction,and neutrophil chemotaxis
A)Histamine
B)Tryptase
C)Prostaglandin D2
D)Leukotriene C4
E)Platelet-activating factor
F)Interleukin-5
G)Tumor necrosis factor-a

Question

Quizplus · Accepted Answer

Prostaglandin D2 (PGD2)is the major arachidonic acid product of the cyclooxygenase pathway in mast cells.PGD2 causes vasodilation and bronchoconstriction,which contribute to the early signs and symptoms of immediate hypersensitivity reactions.It also is a chemoattractant for neutrophils,which accumulate in tissues as part of the late-phase inflammatory response to allergens.

Match the Definitions in Questions with the Mast Cell Mediator