22) The majority of monogenic defects in humans that cause autoimmune diseases are in genes that regulate T cell responses. These include the AIRE, CTLA4, FOXP3, and FAS genes. These findings indicate that B cells and innate immune cells are not important in autoimmunity.

Question

Quizplus · Accepted Answer

While monogenic defects in genes that regulate T cell responses are common in autoimmune diseases, this does not mean that B cells and innate immune cells are not important in autoimmunity. In fact, B cells and innate immune cells have also been implicated in the development of autoimmune diseases, and some monogenic defects in genes that affect these cell types have also been identified.

22) the Majority of Monogenic Defects in Humans That Cause