A mouse is immunized with the tetanus toxoid protein (inactivated toxin) in adjuvant. One week later, the entire population of splenic B cells are isolated from the mouse and mixed with tetanus toxoid-specific CD4 TFH cells plus the purified tetanus toxoid protein. Four days later, the total number of B cells in the culture and the number of tetanus toxoid-specific B cells are determined and compared to the starting population on the day of isolation. The results are shown in Figure Q1) .
B cells preferentially survive and proliferate because:
A) They are the only B cells that express CD40.
B) They are the only B cells that express the receptor for IL-21.
C) They are the only B cells that proliferate in response to their antigen.
D) They are the only B cells presenting the tetanus peptide to the TFH cells.
E) They are the only B cells that received a TLR stimulus during priming.
Correct Answer:
Verified
Q12: Patients with the disease X-linked lymphoproliferative syndrome
Q13: Mice and humans with inactivating mutations in
Q14: The germinal center is a region within
Q15: Individuals with a genetic polymorphism in
Q16: Borrelia hermsii is a spirochete bacterium, transmitted
Q18: The vaccine to Haemophilus influenzae type b
Q19: Studies show that about 50-100 different B
Q20: Infants born with the immunodeficiency disease X-linked
Q21: The upper respiratory tract of many individuals
Q22: Surprisingly, individuals with defects in the early
Unlock this Answer For Free Now!
View this answer and more for free by performing one of the following actions
Scan the QR code to install the App and get 2 free unlocks
Unlock quizzes for free by uploading documents