The pre-B-cell receptor provides an important signal that induces transition of pro-B cells to pre-B cells. An important characteristic of this receptor is that:
A) It signals without binding to an extracellular ligand.
B) It is composed of immunoglobulin heavy chains and the VJ region of a rearranged light chain.
C) It is expressed at very high levels on the surface of the pro-B cell.
D) It signals without requiring association with B-cell receptor signaling subunits, Ig and Ig .
E) It signals without requiring the B-cell receptor signaling kinase, BTK.
Correct Answer:
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