Some Pattern Recognition Receptors (PRRs) recognize nucleic acids, like RNA or DNA. Since our own cells contain human RNA and DNA, the activation of innate immune pathways by these PRRs must rely on additional criteria to discriminate self from nonself. Additional criteria include everything EXCEPT:
A) The subcellular location of the RNA
B) The presence of adenosine residues in viral RNA
C) The methylation state of the DNA
D) Unique structures found on viral RNA
E) The subcellular location of the DNA

Question

Quizplus · Accepted Answer

The presence of adenosine residues in viral RNA is not a criterion used to discriminate self from nonself by Pattern Recognition Receptors (PRRs), as adenosine is a common component of all RNA, both viral and host.

Some Pattern Recognition Receptors (PRRs) Recognize Nucleic Acids, Like RNA