The reaction that catalyzes the addition of an activated two-carbon compound with an activated three-carbon compound is:

Question

Quizplus · Accepted Answer

The reaction described in the question is the initial step in the fatty acid synthesis pathway, where an activated two-carbon compound (acetyl-CoA) and an activated three-carbon compound (malonyl-CoA) are condensed by β-ketoacyl synthase enzyme to form a four-carbon β-ketoacyl intermediate. Malonyl transacylase catalyzes the conversion of acetyl-CoA to malonyl-CoA. β-ketoacyl ACP reductase reduces the β-ketoacyl intermediate to a β-hydroxyacyl intermediate. Acetyl transacylase transfers an acetyl group to the growing fatty acid chain, and enoyl ACP reductase reduces the double bond in the growing fatty acid chain.

The Reaction That Catalyzes the Addition of an Activated Two-Carbon