Which compound inhibits the entry of fatty acyl CoA into the mitochondria as a function of the cell being in the high-energy state?

Question

Quizplus · Accepted Answer

Malonyl CoA inhibits the entry of fatty acyl CoA into the mitochondria through the inhibition of carnitine acyltransferase, which is required for the transport of fatty acyl CoA across the mitochondrial membrane. This inhibition is a mechanism for regulating fatty acid oxidation in response to the energy status of the cell. Therefore, A (malonyl CoA) is the correct answer. C (inhibition of acetyl CoA carboxylase) is also involved in the regulation of fatty acid oxidation but does not directly inhibit the entry of fatty acyl CoA into the mitochondria. B (carnitine acyltransferase) is not a compound but an enzyme involved in the transport of fatty acyl CoA, and its inhibition by malonyl CoA results in the inhibition of fatty acid oxidation. Therefore, D (All of the above) and E (None of the above) are both incorrect.

Which Compound Inhibits the Entry of Fatty Acyl CoA into the Mitochondria