The ΔG˚′ = -21 kJ/mol for the reaction catalyzed by isocitrate dehydrogenase, yet the ΔG˚′ = +29.7 kJ/mol for the reaction catalyzed by malate dehydrogenase. Both of these reactions involve the oxidation of a secondary alcohol. Give an explanation about why the oxidation of isocitrate is so exergonic.

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The Answer of The ΔG˚′ = -21 kJ/mol for the reaction catalyzed by isocitrate dehydrogenase, yet the ΔG˚′ = +29.7 kJ/mol for the reaction catalyzed by malate dehydrogenase. Both of these reactions involve the oxidation of a secondary alcohol. Give an explanation about why the oxidation of isocitrate is so exergonic.

The ΔG˚′ = -21 KJ/mol for the Reaction Catalyzed by Isocitrate