PDH phosphatase deficiency results in which condition?
A) overstimulated PDH
B) low blood glucose
C) chronic elevated plasma lactate
D) high levels of acetyl CoA
E) None of the above.

Question

Quizplus · Accepted Answer

PDH phosphatase deficiency leads to decreased activation of PDH, resulting in reduced glucose uptake and metabolic acidosis. This metabolic acidosis leads to chronic elevated plasma lactate and low blood glucose levels. High levels of acetyl-CoA would not be expected in this condition.

PDH Phosphatase Deficiency Results in Which Condition