Pantothenate kinase associated degeneration:
A) is a predominantly neurological disorder.
B) can cause anemia.
C) effects tissues that are dependent on aerobic metabolism.
D) A and C.
E) A, B, and C.

Question

Quizplus · Accepted Answer

Pantothenate kinase-associated degeneration (PKAN) is a predominantly neurological disorder that affects tissues dependent on aerobic metabolism. It is caused by a mutation in the PANK2 gene which leads to an accumulation of iron in the brain, resulting in neurodegeneration. PKAN can also cause anemia, but it is not a common symptom of the disorder.

Pantothenate Kinase Associated Degeneration