The enzyme responsible for induction of the phosphoinositide cascade is:
A) phospholipase C.
B) phospholipase A.
C) C-dependent protein (CDP).
D) All of the above.
E) None of the above.

Question

Quizplus · Accepted Answer

Phosphoinositide cascade is initiated by the activation of phospholipase C (PLC), which cleaves phosphatidylinositol 4,5-bisphosphate (PIP2) into inositol triphosphate (IP3) and diacylglycerol (DAG), leading to the mobilization of intracellular calcium and activation of protein kinase C (PKC), respectively.

The Enzyme Responsible for Induction of the Phosphoinositide Cascade Is