A common selective estrogen receptor modulator used in breast cancer therapy is:
A) tamoxifen.
B) α-amanitin
C) acetyl-lysine binding protein (ALBP)
D) All of the above
E) None of the above.

Question

Quizplus · Accepted Answer

Tamoxifen is a common selective estrogen receptor modulator (SERM) used in breast cancer therapy. It is a nonsteroidal antiestrogen that competitively binds to the estrogen receptor and thereby prevents the binding of estrogen. This results in the downregulation of estrogen-responsive genes, which can inhibit the growth of estrogen receptor-positive breast cancer cells. Choices B and C are not selective estrogen receptor modulators and are not used in breast cancer therapy.

A Common Selective Estrogen Receptor Modulator Used in Breast Cancer