Through what process might feedback inhibition processes have evolved?

Question

Quizplus · Accepted Answer

Feedback inhibition likely evolved through the linking of specific regulator domains to catalytic domains. This allowed for the regulation of enzyme activity in response to changing substrate and product levels, ultimately leading to the development of feedback inhibition as a means of maintaining metabolic homeostasis. While other processes mentioned (such as gene duplication and the evolution of homologous subunits) may have played a role in the evolution of feedback inhibition, linking regulator domains to catalytic domains is likely the most important factor.

Through What Process Might Feedback Inhibition Processes Have Evolved