Feedback regulation of cholesterol synthesis is mainly controlled at the step catalyzed by the enzyme:

Question

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The feedback regulation of cholesterol synthesis is mainly controlled at the step catalyzed by the enzyme 3-hydroxy-3-methylglutaryl (HMG) CoA reductase. This enzyme is the target of statin drugs, which are used to lower cholesterol levels in the blood. When cholesterol levels in the body are high, feedback inhibition decreases the activity of HMG CoA reductase, thereby reducing the synthesis of cholesterol. This is an important mechanism for maintaining cholesterol homeostasis in the body.

Feedback Regulation of Cholesterol Synthesis Is Mainly Controlled at the Step