Which of the following conditions will activate PDH kinase, which catalyzes the phorphorylation and inactivation of E₁ in the PDH complex? A) elevated concentrations of NADH and ATP B) elevated concentrations of NAD+ and ADP C) Ca²⁺ D) insulin E) elevated concentrations of acetyl CoA

Question

Quizplus · Accepted Answer

PDH kinase is activated by elevated concentrations of ATP and NADH, which indicates that the cell has sufficient energy stores and does not need to produce more acetyl CoA through the TCA cycle. The phosphorylation and inactivation of E1 in the PDH complex helps to regulate this process.

Which of the Following Conditions Will Activate PDH Kinase, Which