You are trying to determine the linkage map of a series of genes, X, Y, and Z, from Caenorhabditis elegans, a nematode worm commonly used in scientific research. From doing several crossover experiments, you know that the recombination frequency between X and Y is 11.5%, between Y and Z is 13%, and between X and Z is 25%. What is a possible sequence of these genes?
A) X-Z-Y
B) Y-Z-X
C) Z-X-Y
D) X-Y-Z

Question

Quizplus · Accepted Answer

The sequence of genes can be determined by their recombination frequencies. The genes with the smallest recombination frequency (11.5% between X and Y) are closest together, while the genes with the largest recombination frequency (25% between X and Z) are furthest apart. Therefore, the sequence is X-Y-Z, where Y is between X and Z.

You Are Trying to Determine the Linkage Map of a Series