Dilated cardiomyopathy (DCM) is a common cause of sudden death and heart failure. Many mutations can cause DCM, but several of them are linked to the protein troponin, which is an essential protein that helps regulate muscle contraction in the heart.
-The A159E mutation causes an A amino acid to be replaced with an E amino acid (their structures are shown here). What type of mutation is the A159E mutation?

Question

Quizplus · Accepted Answer

The A159E mutation is a missense mutation because it results in the substitution of one amino acid (A) with another (E) in the protein sequence.

Dilated Cardiomyopathy (DCM) Is a Common Cause of Sudden Death