Bloom syndrome is a rare disease characterized by growth deficiencies, genomic instability, and the early development of cancers. The BLM gene encodes the BLM protein, which when mutated may result in Bloom syndrome.
-To detect whether or not a cell has a specific region of a gene, researchers add radioactively labeled DNA molecules that can bind to their complementary DNA sequences. To detect a mutant version of the BLM gene, researchers added the radioactive DNA molecule 5' - GCTAGCTAAGCCCA - 3' to cells. What DNA sequence were the researchers trying to detect?

Question

Quizplus · Accepted Answer

The researchers were trying to detect the complementary sequence to the radioactive DNA molecule. The complementary sequence to 5' - GCTAGCTAAGCCCA - 3' is 3' - CGATCGATTCGGGT - 5', which matches choice D.

Bloom Syndrome Is a Rare Disease Characterized by Growth Deficiencies