Cell Membranes Are Asymmetrical

Cell membranes are asymmetrical. Which of the following statements is the most likely explanation for the membrane's asymmetrical nature?

A) Because the cell membrane forms a border between one cell and another in tightly packed tissues such as epithelium, the membrane must be asymmetrical
B) Because cell membranes communicate signals from one organism to another, the cell membranes must be asymmetrical.
C) The two sides of a cell membrane face different environments and carry out different functions.
D) The chemical constitution of the inner and outer layer of the cell membrane is predetermined by genes.
E) Proteins only function on the cytoplasmic side of the cell membrane, which results in the membrane's asymmetrical nature.