Histamines trigger dilation of nearby blood vessels as well as an increase in their permeability, producing

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Histamines trigger dilation of nearby blood vessels, leading to an increased blood flow to the affected area, resulting in redness and heat. Histamines also increase blood vessel permeability, allowing fluid, proteins, and immune cells to leak from the blood vessels into the surrounding tissue, causing swelling. Therefore, the answer is redness, heat, and swelling, as these are all effects of histamine release. Pain is not always associated with histamine release and may depend on the cause of the release.

Histamines Trigger Dilation of Nearby Blood Vessels as Well as an Increase