DNase is an enzyme that catalyzes the hydrolysis of the covalent bonds that join nucleotides together. What would first happen to DNA molecules treated with DNase?

Question

Quizplus · Accepted Answer

DNase catalyzes the hydrolysis of phosphodiester bonds between deoxyribose sugars in DNA molecules. This would result in the breaking of the sugar-phosphate backbone of the DNA molecule, leading to the release of individual nucleotides. The two strands of the double helix would then separate as a result of the loss of the phosphodiester bonds holding them together. Therefore, option B is the correct answer.

DNase Is an Enzyme That Catalyzes the Hydrolysis of the Covalent