Let Us Suppose That Someone Is Successful at Producing Induced

Let us suppose that someone is successful at producing induced pluripotent stem cells (iPS) for replacement of pancreatic insulin-producing cells for people with type 1 diabetes. Which of the following occurrences could still be problematic?

A) the possibility that, once introduced into the patient, the iPS cells produce nonpancreatic cells
B) the success of the iPS cells taking up residence in the pancreas
C) the ability of the iPS cells to respond to appropriate regulatory signals
D) the possibility that, once introduced into the patient, the iPS cells produce only pancreatic cells