When DNA is compacted by histones into 10-nm and 30-nm fibers, the DNA is unable to interact with proteins required for gene expression. Therefore, to allow for these proteins to act, the chromatin must constantly alter its structure. Which processes contribute to this dynamic activity?

Question

Quizplus · Accepted Answer

DNA methylation and phosphorylation of histone tails are processes that can alter the structure of chromatin and allow for interactions between DNA and proteins required for gene expression. Hydrolysis of DNA molecules and binding of an inducer to a repressor molecule are not directly involved in altering the structure of chromatin. And while accessibility of heterochromatin to phosphorylating enzymes can contribute to altering chromatin structure, it is not the only process involved.

When DNA Is Compacted by Histones into 10-Nm and 30-Nm