Which of the following is the best definition of autoimmune disease?
A) A condition in which B and T cells trigger anaphylactic shock in response to an antigen.
B) A condition in which the adaptive immune system fails to recognise the second infection by the same antigen.
C) A condition in which self molecules are treated as nonself (loss of self-tolerance).
D) A condition in which the immune system creates random antibodies without being triggered by a specific antigen.

Question

Quizplus · Accepted Answer

Autoimmune disease is a condition in which the immune system mistakenly attacks healthy tissues because it loses its ability to distinguish between self and non-self molecules, which is called loss of self-tolerance. Option A describes anaphylactic shock, which is a severe life-threatening allergic reaction. Option B refers to the phenomenon of memory cells not recognizing the same antigen in secondary infections, which is the basis of vaccination. Option D describes random production of antibodies, which is not associated with autoimmune diseases.

Which of the Following Is the Best Definition of Autoimmune