Tay-Sachs disease is a human genetic abnormality that results in cells accumulating and becoming clogged with very large, complex, undigested lipids. Which cellular organelle is most likely defective in this condition?
A) the lysosome
B) the Golgi apparatus
C) the smooth endoplasmic reticulum
D) the rough endoplasmic reticulum

Question

Quizplus · Accepted Answer

Lysosomes are responsible for breaking down and digesting lipids, among other cellular waste products. In Tay-Sachs disease, there is a deficiency in the enzyme necessary to break down a specific lipid, resulting in accumulation of undigested lipids in the lysosomes. Therefore, the lysosome is most likely the defective organelle in Tay-Sachs disease.

Tay-Sachs Disease Is a Human Genetic Abnormality That Results in Cells